EBV Target gene Detail Information

> WBP1L Gene Search Result

Gene Information

Gene Name	WBP1L
Gene ID	54838
Gene Alias	OPA1L; OPAL1; C10orf26
Transcripts	ENSG00000166272
Virus	EBV
Gene Type	protein coding
HPA Location Info	Microtubules;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	Q9NX94
HGNC ID	HGNC:23510
VEGA ID	OTTHUMG00000018968
OMIM ID	611129
String ID	9606.ENSP00000414721
PharmGKB ID	PA128394674

Target gene [WBP1L] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
3000078	chr10	235	9	10	254	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE102203 (GEO)	B-cell lymphoma	9	Plasmablastic lymphomas (EBV+)(6), Plasmablastic lymphomas (EBV-)(3)
GSE100458 (GEO)	Burkitt lymphoma	14	Burkitt lyphoma cell line Akata(EBV+)(2),Burkitt lyphoma cell line Akata(EBV-)(2),Burkitt lyphoma cell line Awia(EBV+)(2),Burkitt lyphoma cell line Awia(EBV-)(2),Burkitt lyphoma cell line Eli(EBV+)(1),Burkitt lyphoma cell line Eli(EBV-)(1),Burkitt lyphoma cell line Mutu(EBV+)(2),Burkitt lyphoma cell line Mutu(EBV-)(2)
GSE42867 (GEO)	Burkitt lymphoma	12	Burkitt lymphoma cell line Awia (EBV+)(12)
GSE85599 (GEO)	Infectious mononucleosis	17	Chronic active EBV infection (EBV+)(5), Acute infectious mononucleosis (EBV+)(6), Normal (6)
GSE12452 (GEO)	Nasopharyngeal carcinoma	41	Nasopharyngeal carcinoma (EBV+)(31), Normal(10)

> Dataset: GSE102203
HeatMap of cell type fractions in all samples	Lollipop of WBP1L expression and immune infiltrating cell level correlation result in EBV+ samples
WBP1L expression: Low -> High

> Dataset: GSE100458
HeatMap of cell type fractions in all samples	Lollipop of WBP1L expression and immune infiltrating cell level correlation result in EBV+ samples
WBP1L expression: Low -> High

> Dataset: GSE42867
HeatMap of cell type fractions in all samples	Lollipop of WBP1L expression and immune infiltrating cell level correlation result in EBV+ samples
WBP1L expression: Low -> High

> Dataset: GSE85599
HeatMap of cell type fractions in all samples	Lollipop of WBP1L expression and immune infiltrating cell level correlation result in EBV+ samples
WBP1L expression: Low -> High

> Dataset: GSE12452
HeatMap of cell type fractions in all samples	Lollipop of WBP1L expression and immune infiltrating cell level correlation result in EBV+ samples
WBP1L expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).

> Dataset: GSE102203