HBV Target gene Detail Information

> VWA5B1 Gene Search Result

Gene Information

Gene Name	VWA5B1
Gene ID	127731
Gene Full Name	von Willebrand factor A domain containing 5B1
Transcripts	ENSG00000158816
Virus	HBV
Gene Type	protein coding
HPA Location Info	Mitochondria;Cytosol;Plasma membrane;Predicted to be secreted;
HPA Protein Class Info	Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID	Q5TIE3
HGNC ID	HGNC:26538
VEGA ID	OTTHUMG00000002835
String ID	9606.ENSP00000364220
PharmGKB ID	PA162409030

Target gene [VWA5B1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1015372	chr1		2		2	View
1400281	chr1	5			5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of VWA5B1 expression and immune infiltrating cell level correlation result in HBV+ samples
VWA5B1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).