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HPV Target gene Detail Information

> VSTM2A Gene Search Result


Gene Information
Gene Name VSTM2A
Gene ID 222008
Gene Full Name V-set and transmembrane domain containing 2A
Gene Alias VSTM2
Transcripts ENSG00000170419
Virus HPV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Plasma proteins, Predicted secreted proteins
Uniport_ID Q8TAG5
HGNC ID HGNC:28499
VEGA ID OTTHUMG00000129271
String ID 9606.ENSP00000384103
PharmGKB ID PA162408875
Target gene [VSTM2A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5004219 chr7 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of VSTM2A expression and immune infiltrating cell level correlation result in HPV+ samples
VSTM2A expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of VSTM2A expression and immune infiltrating cell level correlation result in HPV+ samples
VSTM2A expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of VSTM2A expression and immune infiltrating cell level correlation result in HPV+ samples
VSTM2A expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of VSTM2A expression and immune infiltrating cell level correlation result in HPV+ samples
VSTM2A expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of VSTM2A expression and immune infiltrating cell level correlation result in HPV+ samples
VSTM2A expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).