HIV Target gene Detail Information

> VPS8 Gene Search Result

Gene Information

Gene Name	VPS8
Gene ID	23355
Gene Full Name	VPS8, CORVET complex subunit
Gene Alias	KIAA0804
Transcripts	ENSG00000156931
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8N3P4
HGNC ID	HGNC:29122
VEGA ID	OTTHUMG00000156707
OMIM ID	618366
String ID	9606.ENSP00000404704
PharmGKB ID	PA142671617

Target gene [VPS8] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001940	chr3	118	4		122	View
4001994	chr3	117	2		119	View
4002162	chr3	107	2		109	View
4002178	chr3	107	1		108	View
4003459	chr3	12	8	41	61	View
4005952	chr3	5		23	28	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of VPS8 expression and immune infiltrating cell level correlation result in HIV+ samples
VPS8 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of VPS8 expression and immune infiltrating cell level correlation result in HIV+ samples
VPS8 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).