HIV Target gene Detail Information

> VPS53 Gene Search Result

Gene Information

Gene Name	VPS53
Gene ID	55275
Gene Full Name	VPS53, GARP complex subunit
Gene Alias	HCCS1; PCH2E; hVps53L; pp13624
Transcripts	ENSG00000283883
Virus	HIV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Vesicles;Cytosol;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	Q5VIR6
HGNC ID	HGNC:25608
VEGA ID	OTTHUMG00000177441
OMIM ID	615850
String ID	9606.ENSP00000401435
PharmGKB ID	PA142670618

Target gene [VPS53] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005345	chr17	25	7	1	33	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of VPS53 expression and immune infiltrating cell level correlation result in HIV+ samples
VPS53 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).