HBV Target gene Detail Information

> VKORC1L1 Gene Search Result


Gene Information
Gene Name VKORC1L1
Gene ID 154807
Gene Full Name vitamin K epoxide reductase complex subunit 1 like 1
Transcripts ENSG00000196715
Virus HBV
Gene Type protein coding
HPA Location Info Endoplasmic reticulum;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Enzymes, FDA approved drug targets, Predicted membrane proteins
Uniport_ID Q8N0U8
HGNC ID HGNC:21492
VEGA ID OTTHUMG00000129449
OMIM ID 608838
String ID 9606.ENSP00000403077
Drugbank ID BE0002329
PharmGKB ID PA134931578
Target gene [VKORC1L1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1015390 chr7 2 2 View
1016128 chr7 2 2 View
1016485 chr7 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of VKORC1L1 expression and immune infiltrating cell level correlation result in HBV+ samples
VKORC1L1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).