HBV Target gene Detail Information

> VKORC1L1 Gene Search Result

Gene Information

Gene Name	VKORC1L1
Gene ID	154807
Gene Full Name	vitamin K epoxide reductase complex subunit 1 like 1
Transcripts	ENSG00000196715
Virus	HBV
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Enzymes, FDA approved drug targets, Predicted membrane proteins
Uniport_ID	Q8N0U8
HGNC ID	HGNC:21492
VEGA ID	OTTHUMG00000129449
OMIM ID	608838
String ID	9606.ENSP00000403077
Drugbank ID	BE0002329
PharmGKB ID	PA134931578

Target gene [VKORC1L1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1015390	chr7	2			2	View
1016128	chr7	2			2	View
1016485	chr7	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of VKORC1L1 expression and immune infiltrating cell level correlation result in HBV+ samples
VKORC1L1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).