HTLV1 Target gene Detail Information

> VGF Gene Search Result

Gene Information

Gene Name	VGF
Gene ID	7425
Gene Full Name	VGF nerve growth factor inducible
Gene Alias	SCG7; SgVII
Transcripts	ENSG00000128564
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Vesicles;Predicted to be secreted;
HPA Protein Class Info	Plasma proteins, Predicted secreted proteins
Uniport_ID	O15240
HGNC ID	HGNC:12684
VEGA ID	OTTHUMG00000157109
OMIM ID	602186
String ID	9606.ENSP00000249330
PharmGKB ID	PA37305

Target gene [VGF] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6003323	chr7	99	68		167	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of VGF expression and immune infiltrating cell level correlation result in HTLV1+ samples
VGF expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of VGF expression and immune infiltrating cell level correlation result in HTLV1+ samples
VGF expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of VGF expression and immune infiltrating cell level correlation result in HTLV1+ samples
VGF expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).