HIV Target gene Detail Information

> VAV3 Gene Search Result

Gene Information

Gene Name	VAV3
Gene ID	10451
Gene Full Name	vav guanine nucleotide exchange factor 3
Transcripts	ENSG00000134215
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	Q9UKW4
HGNC ID	HGNC:12659
VEGA ID	OTTHUMG00000010995
OMIM ID	605541
String ID	9606.ENSP00000359073
PharmGKB ID	PA37282

Target gene [VAV3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006853	chr1	22			22	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of VAV3 expression and immune infiltrating cell level correlation result in HIV+ samples
VAV3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of VAV3 expression and immune infiltrating cell level correlation result in HIV+ samples
VAV3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).