HIV Target gene Detail Information

> VAPB Gene Search Result

Gene Information

Gene Name	VAPB
Gene ID	9217
Gene Full Name	VAMP associated protein B and C
Gene Alias	ALS8; VAP-B; VAMP-B
Transcripts	ENSG00000124164
Virus	HIV
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	O95292
HGNC ID	HGNC:12649
VEGA ID	OTTHUMG00000032840
OMIM ID	605704
String ID	9606.ENSP00000417175
PharmGKB ID	PA37273

Target gene [VAPB] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005087	chr20	28	8		36	View
4015534	chr20	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of VAPB expression and immune infiltrating cell level correlation result in HIV+ samples
VAPB expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).