HTLV1 Target gene Detail Information

> VAMP4 Gene Search Result


Gene Information
Gene Name VAMP4
Gene ID 8674
Gene Full Name vesicle associated membrane protein 4
Gene Alias VAMP-4; VAMP24
Transcripts ENSG00000117533
Virus HTLV1
Gene Type protein coding
HPA Location Info Golgi apparatus;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted membrane proteins
Uniport_ID O75379
HGNC ID HGNC:12645
VEGA ID OTTHUMG00000034788
OMIM ID 606909
String ID 9606.ENSP00000236192
PharmGKB ID PA37269
Target gene [VAMP4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6002807 chr1 79 29 100 208 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of VAMP4 expression and immune infiltrating cell level correlation result in HTLV1+ samples
VAMP4 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of VAMP4 expression and immune infiltrating cell level correlation result in HTLV1+ samples
VAMP4 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of VAMP4 expression and immune infiltrating cell level correlation result in HTLV1+ samples
VAMP4 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).