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HIV Target gene Detail Information

> UVRAG Gene Search Result


Gene Information
Gene Name UVRAG
Gene ID 7405
Gene Full Name UV radiation resistance associated
Gene Alias p63; DHTX; VPS38
Transcripts ENSG00000198382
Virus HIV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Disease related genes, Predicted intracellular proteins
Gene Function Suppressor gene
Uniport_ID Q9P2Y5
HGNC ID HGNC:12640
VEGA ID OTTHUMG00000165319
OMIM ID 602493
String ID 9606.ENSP00000348455
PharmGKB ID PA37264
Target gene [UVRAG] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000672 chr11 265 41 18 324 View
4007310 chr11 8 9 3 20 View
4008872 chr11 5 7 1 13 View
4009367 chr11 12 12 View
4010673 chr11 7 1 8 View
4011513 chr11 1 3 2 6 View
4013970 chr11 1 1 1 3 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of UVRAG expression and immune infiltrating cell level correlation result in HIV+ samples
UVRAG expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of UVRAG expression and immune infiltrating cell level correlation result in HIV+ samples
UVRAG expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).