HIV Target gene Detail Information

> USPL1 Gene Search Result

Gene Information

Gene Name	USPL1
Gene ID	10208
Gene Full Name	ubiquitin specific peptidase like 1
Gene Alias	C13orf22; D13S106E; bA121O19.1
Transcripts	ENSG00000132952
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q5W0Q7
HGNC ID	HGNC:20294
VEGA ID	OTTHUMG00000016675
OMIM ID	617470
String ID	9606.ENSP00000255304
PharmGKB ID	PA134872379

Target gene [USPL1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005902	chr13	20	8		28	View
4005941	chr13	19	9		28	View
4010166	chr13	5	4		9	View
4016585	chr13				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of USPL1 expression and immune infiltrating cell level correlation result in HIV+ samples
USPL1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of USPL1 expression and immune infiltrating cell level correlation result in HIV+ samples
USPL1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).