HIV Target gene Detail Information

> USP42 Gene Search Result

Gene Information

Gene Name	USP42
Gene ID	84132
Gene Full Name	ubiquitin specific peptidase 42
Transcripts	ENSG00000106346
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q9H9J4
HGNC ID	HGNC:20068
VEGA ID	OTTHUMG00000151888
String ID	9606.ENSP00000301962
PharmGKB ID	PA134902515

Target gene [USP42] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003826	chr7	53	1		54	View
4003996	chr7	51			51	View
4005076	chr7	36			36	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of USP42 expression and immune infiltrating cell level correlation result in HIV+ samples
USP42 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of USP42 expression and immune infiltrating cell level correlation result in HIV+ samples
USP42 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).