HBV Target gene Detail Information

> USP40 Gene Search Result


Gene Information
Gene Name USP40
Gene ID 55230
Gene Full Name ubiquitin specific peptidase 40
Transcripts ENSG00000085982
Virus HBV
Gene Type protein coding
HPA Location Info Vesicles;Focal adhesion sites;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID Q9NVE5
HGNC ID HGNC:20069
VEGA ID OTTHUMG00000153199
OMIM ID 610570
String ID 9606.ENSP00000415434
PharmGKB ID PA134909324
Target gene [USP40] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002727 chr2 71 85 66 222 View
1004402 chr2 34 39 10 83 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of USP40 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
USP40 expression: Low -> High
Lollipop of USP40 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of USP40 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of USP40 expression and immune infiltrating cell level correlation result in HBV+ samples
USP40 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).