HIV Target gene Detail Information

> USP36 Gene Search Result

Gene Information

Gene Name	USP36
Gene ID	57602
Gene Full Name	ubiquitin specific peptidase 36
Gene Alias	DUB1
Transcripts	ENSG00000055483
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoli;Nucleoli rim;Nuclear speckles;
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q9P275
HGNC ID	HGNC:20062
VEGA ID	OTTHUMG00000177542
OMIM ID	612543
String ID	9606.ENSP00000441214
PharmGKB ID	PA134949090

Target gene [USP36] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000516	chr17	194	189	22	405	View
4004583	chr17	14	1	27	42	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of USP36 expression and immune infiltrating cell level correlation result in HIV+ samples
USP36 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of USP36 expression and immune infiltrating cell level correlation result in HIV+ samples
USP36 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).