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HTLV1 Target gene Detail Information

> USP16 Gene Search Result


Gene Information
Gene Name USP16
Gene ID 10600
Gene Full Name ubiquitin specific peptidase 16
Gene Alias UBPM; UBP-M
Transcripts ENSG00000156256
Virus HTLV1
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;
HPA Protein Class Info Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID Q9Y5T5
HGNC ID HGNC:12614
VEGA ID OTTHUMG00000078802
OMIM ID 604735
String ID 9606.ENSP00000334808
PharmGKB ID PA37240
Target gene [USP16] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6000506 chr21 1378 17 1 1396 View
6004704 chr12 104 3 107 View
6006212 chr12 42 18 13 73 View
6019916 chr12 4 2 1 7 View
6024211 chr12 2 1 3 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of USP16 expression and immune infiltrating cell level correlation result in HTLV1+ samples
USP16 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of USP16 expression and immune infiltrating cell level correlation result in HTLV1+ samples
USP16 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of USP16 expression and immune infiltrating cell level correlation result in HTLV1+ samples
USP16 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).