HIV Target gene Detail Information

> USP15 Gene Search Result

Gene Information

Gene Name	USP15
Gene ID	9958
Gene Full Name	ubiquitin specific peptidase 15
Gene Alias	UNPH4; UNPH-2
Transcripts	ENSG00000135655
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q9Y4E8
HGNC ID	HGNC:12613
VEGA ID	OTTHUMG00000170186
OMIM ID	604731
String ID	9606.ENSP00000280377
PharmGKB ID	PA37239

Target gene [USP15] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001500	chr12	142	11	4	157	View
4005651	chr12	26	3	1	30	View
4008274	chr12	9	7		16	View
4008598	chr12	9	5		14	View
4008874	chr12	10	3		13	View
4012704	chr12	1	3		4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of USP15 expression and immune infiltrating cell level correlation result in HIV+ samples
USP15 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).