HIV Target gene Detail Information

> USP14 Gene Search Result

Gene Information

Gene Name	USP14
Gene ID	9097
Gene Full Name	ubiquitin specific peptidase 14
Gene Alias	TGT
Transcripts	ENSG00000101557
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	P54578
HGNC ID	HGNC:12612
VEGA ID	OTTHUMG00000178040
OMIM ID	607274
String ID	9606.ENSP00000261601
Drugbank ID	BE0008965
PharmGKB ID	PA37238

Target gene [USP14] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005536	chr18	29	2		31	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of USP14 expression and immune infiltrating cell level correlation result in HIV+ samples
USP14 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of USP14 expression and immune infiltrating cell level correlation result in HIV+ samples
USP14 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).