HIV Target gene Detail Information

> USP13 Gene Search Result

Gene Information

Gene Name	USP13
Gene ID	8975
Gene Full Name	ubiquitin specific peptidase 13
Gene Alias	ISOT3; IsoT-3
Transcripts	ENSG00000058056
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q92995
HGNC ID	HGNC:12611
VEGA ID	OTTHUMG00000157783
OMIM ID	603591
String ID	9606.ENSP00000263966
PharmGKB ID	PA37237

Target gene [USP13] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009303	chr3	12			12	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of USP13 expression and immune infiltrating cell level correlation result in HIV+ samples
USP13 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of USP13 expression and immune infiltrating cell level correlation result in HIV+ samples
USP13 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).