HIV Target gene Detail Information

> USP10 Gene Search Result

Gene Information

Gene Name	USP10
Gene ID	9100
Gene Full Name	ubiquitin specific peptidase 10
Gene Alias	UBPO
Transcripts	ENSG00000103194
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q14694
HGNC ID	HGNC:12608
VEGA ID	OTTHUMG00000176770
OMIM ID	609818
String ID	9606.ENSP00000457411
PharmGKB ID	PA37234

Target gene [USP10] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003096	chr16	61	7	1	69	View
4003373	chr16	52	11		63	View
4005494	chr16	29	3		32	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of USP10 expression and immune infiltrating cell level correlation result in HIV+ samples
USP10 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of USP10 expression and immune infiltrating cell level correlation result in HIV+ samples
USP10 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).