HBV Target gene Detail Information

> USH2A Gene Search Result


Gene Information
Gene Name USH2A
Gene ID 7399
Gene Full Name usherin
Gene Alias US2; RP39; USH2; dJ1111A8.1
Transcripts ENSG00000042781
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Predicted membrane proteins
Uniport_ID O75445
HGNC ID HGNC:12601
VEGA ID OTTHUMG00000037079
OMIM ID 608400
String ID 9606.ENSP00000305941
PharmGKB ID PA37228
Target gene [USH2A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1014449 chr1 2 1 3 View
1402341 chr1 2 1 3 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of USH2A expression and immune infiltrating cell level correlation result in HBV+ samples
USH2A expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).