HTLV1 Target gene Detail Information

> URB1 Gene Search Result

Gene Information

Gene Name	URB1
Gene ID	9875
Gene Full Name	URB1 ribosome biogenesis homolog
Gene Alias	NPA1; C21orf108
Transcripts	ENSG00000142207
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nucleoli fibrillar center;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	O60287
HGNC ID	HGNC:17344
VEGA ID	OTTHUMG00000064919
OMIM ID	608865
String ID	9606.ENSP00000372199
PharmGKB ID	PA162408676

Target gene [URB1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6005167	chr21	42	46	6	94	View
6012610	chr21	17	4	1	22	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of URB1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
URB1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).