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HBV Target gene Detail Information

> UNC5D Gene Search Result


Gene Information
Gene Name UNC5D
Gene ID 137970
Gene Full Name unc-5 netrin receptor D
Gene Alias Unc5h4; PRO34692
Transcripts ENSG00000156687
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Gene Function Suppressor gene
Uniport_ID Q6UXZ4
HGNC ID HGNC:18634
VEGA ID OTTHUMG00000157145
OMIM ID 616466
String ID 9606.ENSP00000385143
PharmGKB ID PA38612
Target gene [UNC5D] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1009095 chr8 17 17 View
1013685 chr8 3 1 4 View
1013702 chr8 3 1 4 View
1016237 chr8 1 1 View
1016628 chr8 1 1 View
1016632 chr8 1 1 View
1016733 chr8 1 1 View
1019728 chr8 0 View
1400196 chr8 1 1 View
1401848 chr8 1 1 View
1403012 chr8 3 1 4 View
1403013 chr8 17 17 View
1403844 chr8 3 1 4 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of UNC5D expression and immune infiltrating cell level correlation result in HBV+ samples
UNC5D expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).