Home
Virus
Gene
Disease
Dataset
Download
Help
 
HBV Target gene Detail Information

> UNC5C Gene Search Result


Gene Information
Gene Name UNC5C
Gene ID 8633
Gene Full Name unc-5 netrin receptor C
Gene Alias UNC5H3
Transcripts ENSG00000182168
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Gene Function Suppressor gene
Uniport_ID O95185
HGNC ID HGNC:12569
VEGA ID OTTHUMG00000130989
OMIM ID 603610
String ID 9606.ENSP00000406022
PharmGKB ID PA37206
Target gene [UNC5C] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1015509 chr4 2 2 View
1400385 chr4 9 5 2 16 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of UNC5C expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
UNC5C expression: Low -> High
Lollipop of UNC5C expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of UNC5C expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of UNC5C expression and immune infiltrating cell level correlation result in HBV+ samples
UNC5C expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).