HIV Target gene Detail Information

> UHRF1 Gene Search Result

Gene Information

Gene Name	UHRF1
Gene ID	29128
Gene Full Name	ubiquitin like with PHD and ring finger domains 1
Gene Alias	Np95; hNP95; ICBP90; RNF106; TDRD22; hUHRF1; huNp95
Transcripts	ENSG00000276043
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	Q96T88
HGNC ID	HGNC:12556
VEGA ID	OTTHUMG00000180251
OMIM ID	607990
String ID	9606.ENSP00000479617
PharmGKB ID	PA37196

Target gene [UHRF1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009110	chr19	12			12	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of UHRF1 expression and immune infiltrating cell level correlation result in HIV+ samples
UHRF1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of UHRF1 expression and immune infiltrating cell level correlation result in HIV+ samples
UHRF1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).