HPV Target gene Detail Information

> UGT2B28 Gene Search Result

Gene Information

Gene Name	UGT2B28
Gene ID	54490
Gene Full Name	UDP glucuronosyltransferase family 2 member B28
Transcripts	ENSG00000135226
Virus	HPV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Enzymes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q9BY64
HGNC ID	HGNC:13479
VEGA ID	OTTHUMG00000129401
OMIM ID	606497
String ID	9606.ENSP00000334276
PharmGKB ID	PA37779

Target gene [UGT2B28] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5403930	chr4	1	1		2	View
5404284	chr4	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE140662 (GEO)	Condyloma Acuminatum	8	Condyloma acuminata (HPV+)(5), Skin(3)
GSE65858 (GEO)	Head and neck squamous cell carcinoma	270	Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE51993 (GEO)	Cervical intraepithelial neoplasia	24	Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662
HeatMap of cell type fractions in all samples	Lollipop of UGT2B28 expression and immune infiltrating cell level correlation result in HPV+ samples
UGT2B28 expression: Low -> High

> Dataset: GSE65858
HeatMap of cell type fractions in all samples	Lollipop of UGT2B28 expression and immune infiltrating cell level correlation result in HPV+ samples
UGT2B28 expression: Low -> High

> Dataset: GSE51993
HeatMap of cell type fractions in all samples	Lollipop of UGT2B28 expression and immune infiltrating cell level correlation result in HPV+ samples
UGT2B28 expression: Low -> High

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of UGT2B28 expression and immune infiltrating cell level correlation result in HPV+ samples
UGT2B28 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).