HTLV1 Target gene Detail Information

> UGCG Gene Search Result


Gene Information
Gene Name UGCG
Gene ID 7357
Gene Full Name UDP-glucose ceramide glucosyltransferase
Gene Alias GCS; GLCT1
Transcripts ENSG00000148154
Virus HTLV1
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Enzymes, FDA approved drug targets, Predicted membrane proteins, Transporters
Uniport_ID Q16739
HGNC ID HGNC:12524
VEGA ID OTTHUMG00000020498
OMIM ID 602874
String ID 9606.ENSP00000363397
Drugbank ID BE0000477
PharmGKB ID PA37169
Target gene [UGCG] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6000492 chr9 1184 197 46 1427 View
6011855 chr9 17 8 25 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of UGCG expression and immune infiltrating cell level correlation result in HTLV1+ samples
UGCG expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of UGCG expression and immune infiltrating cell level correlation result in HTLV1+ samples
UGCG expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of UGCG expression and immune infiltrating cell level correlation result in HTLV1+ samples
UGCG expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).