HTLV1 Target gene Detail Information

> UGCG Gene Search Result

Gene Information

Gene Name	UGCG
Gene ID	7357
Gene Full Name	UDP-glucose ceramide glucosyltransferase
Gene Alias	GCS; GLCT1
Transcripts	ENSG00000148154
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Enzymes, FDA approved drug targets, Predicted membrane proteins, Transporters
Uniport_ID	Q16739
HGNC ID	HGNC:12524
VEGA ID	OTTHUMG00000020498
OMIM ID	602874
String ID	9606.ENSP00000363397
Drugbank ID	BE0000477
PharmGKB ID	PA37169

Target gene [UGCG] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6000492	chr9	1184	197	46	1427	View
6011855	chr9	17	8		25	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of UGCG expression and immune infiltrating cell level correlation result in HTLV1+ samples
UGCG expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of UGCG expression and immune infiltrating cell level correlation result in HTLV1+ samples
UGCG expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of UGCG expression and immune infiltrating cell level correlation result in HTLV1+ samples
UGCG expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).