HBV Target gene Detail Information

> UBE4B Gene Search Result

Gene Information

Gene Name	UBE4B
Gene ID	10277
Gene Full Name	ubiquitination factor E4B
Gene Alias	E4; UFD2; HDNB1; UBOX3; UFD2A
Transcripts	ENSG00000130939
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	O95155
HGNC ID	HGNC:12500
VEGA ID	OTTHUMG00000001797
OMIM ID	613565
String ID	9606.ENSP00000343001
PharmGKB ID	PA37148

Target gene [UBE4B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001305	chr1	626	44	121	791	View
1006831	chr1	32	1		33	View
1010592	chr1	11			11	View
1403624	chr1	11			11	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of UBE4B expression and immune infiltrating cell level correlation result in HBV+ samples
UBE4B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).