HIV Target gene Detail Information

> UBE2R2 Gene Search Result

Gene Information

Gene Name	UBE2R2
Gene ID	54926
Gene Full Name	ubiquitin conjugating enzyme E2 R2
Gene Alias	UBC3B; CDC34B; E2-CDC34B
Transcripts	ENSG00000107341
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoli;Nucleoplasm;Cytosol;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q712K3
HGNC ID	HGNC:19907
VEGA ID	OTTHUMG00000019797
OMIM ID	612506
String ID	9606.ENSP00000263228
PharmGKB ID	PA134946881

Target gene [UBE2R2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004016	chr9	6	43	2	51	View
4004617	chr9	37	2	2	41	View
4008188	chr9	13	3		16	View
4012020	chr9	4	1		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of UBE2R2 expression and immune infiltrating cell level correlation result in HIV+ samples
UBE2R2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of UBE2R2 expression and immune infiltrating cell level correlation result in HIV+ samples
UBE2R2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).