HIV Target gene Detail Information

> UBE2K Gene Search Result


Gene Information
Gene Name UBE2K
Gene ID 3093
Gene Full Name ubiquitin conjugating enzyme E2 K
Gene Alias LIG; HIP2; HYPG; UBC1; E2-25K
Transcripts ENSG00000078140
Virus HIV
Gene Type protein coding
HPA Location Info Cytosol;Plasma membrane;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID P61086
HGNC ID HGNC:4914
VEGA ID OTTHUMG00000160543
OMIM ID 602846
String ID 9606.ENSP00000261427
PharmGKB ID PA162407874
Target gene [UBE2K] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4003885 chr4 41 11 1 53 View
4005760 chr4 20 7 3 30 View
4007738 chr4 17 1 18 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of UBE2K expression and immune infiltrating cell level correlation result in HIV+ samples
UBE2K expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).