HIV Target gene Detail Information

> UBE2I Gene Search Result

Gene Information

Gene Name	UBE2I
Gene ID	7329
Gene Full Name	ubiquitin conjugating enzyme E2 I
Gene Alias	P18; UBC9; C358B7.1
Transcripts	ENSG00000103275
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters
Uniport_ID	P63279
HGNC ID	HGNC:12485
VEGA ID	OTTHUMG00000186701
OMIM ID	601661
String ID	9606.ENSP00000348056
PharmGKB ID	PA37134

Target gene [UBE2I] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005747	chr16	28	2		30	View
4006530	chr16	23	1		24	View
4008680	chr16	11	3		14	View
4009375	chr16	11	1		12	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of UBE2I expression and immune infiltrating cell level correlation result in HIV+ samples
UBE2I expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of UBE2I expression and immune infiltrating cell level correlation result in HIV+ samples
UBE2I expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).