HIV Target gene Detail Information

> UBE2G2 Gene Search Result


Gene Information
Gene Name UBE2G2
Gene ID 7327
Gene Full Name ubiquitin conjugating enzyme E2 G2
Gene Alias UBC7
Transcripts ENSG00000184787
Virus HIV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID P60604
HGNC ID HGNC:12483
VEGA ID OTTHUMG00000089179
OMIM ID 603124
String ID 9606.ENSP00000338348
PharmGKB ID PA37132
Target gene [UBE2G2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4300049 chr21 39 1 40 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of UBE2G2 expression and immune infiltrating cell level correlation result in HIV+ samples
UBE2G2 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of UBE2G2 expression and immune infiltrating cell level correlation result in HIV+ samples
UBE2G2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).