HIV Target gene Detail Information

> UBE2G1 Gene Search Result

Gene Information

Gene Name	UBE2G1
Gene ID	7326
Gene Full Name	ubiquitin conjugating enzyme E2 G1
Gene Alias	UBC7; E217K; UBE2G
Transcripts	ENSG00000132388
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	P62253
HGNC ID	HGNC:12482
VEGA ID	OTTHUMG00000177826
OMIM ID	601569
String ID	9606.ENSP00000380178
PharmGKB ID	PA37131

Target gene [UBE2G1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000818	chr17	184	55	34	273	View
4001722	chr17	99	28	10	137	View
4001868	chr17	61	13	52	126	View
4001891	chr17	113	9	2	124	View
4001916	chr17	36	48	39	123	View
4002605	chr17	38	19	30	87	View
4003256	chr17	22	27	16	65	View
4006394	chr17	25			25	View
4007087	chr17	18	3		21	View
4007446	chr17	17	1	1	19	View
4008004	chr17	8	9		17	View
4008640	chr17	13	1		14	View
4010117	chr17	3	5	2	10	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of UBE2G1 expression and immune infiltrating cell level correlation result in HIV+ samples
UBE2G1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of UBE2G1 expression and immune infiltrating cell level correlation result in HIV+ samples
UBE2G1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).