HIV Target gene Detail Information

> UBE2E2 Gene Search Result

Gene Information

Gene Name	UBE2E2
Gene ID	7325
Gene Full Name	ubiquitin conjugating enzyme E2 E2
Gene Alias	UBCH8
Transcripts	ENSG00000182247
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q96LR5
HGNC ID	HGNC:12478
VEGA ID	OTTHUMG00000130482
OMIM ID	602163
String ID	9606.ENSP00000379931
PharmGKB ID	PA37128

Target gene [UBE2E2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009255	chr3	11		1	12	View
4011751	chr3		6		6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of UBE2E2 expression and immune infiltrating cell level correlation result in HIV+ samples
UBE2E2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of UBE2E2 expression and immune infiltrating cell level correlation result in HIV+ samples
UBE2E2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).