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HBV Target gene Detail Information

> UBB Gene Search Result


Gene Information
Gene Name UBB
Gene ID 7314
Gene Full Name ubiquitin B
Gene Alias HEL-S-50
Transcripts ENSG00000170315
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID P0CG47
HGNC ID HGNC:12463
VEGA ID OTTHUMG00000058987
OMIM ID 191339
String ID 9606.ENSP00000304697
Drugbank ID BE0004560
PharmGKB ID PA37113
Target gene [UBB] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000393 chr17 2445 77 3 2525 View
1002273 chr17 271 32 303 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of UBB expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
UBB expression: Low -> High
Lollipop of UBB expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of UBB expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of UBB expression and immune infiltrating cell level correlation result in HBV+ samples
UBB expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).