HIV Target gene Detail Information

> UBASH3B Gene Search Result

Gene Information

Gene Name	UBASH3B
Gene ID	84959
Gene Full Name	ubiquitin associated and SH3 domain containing B
Gene Alias	p70; STS1; STS-1; TULA2; TULA-2
Transcripts	ENSG00000154127
Virus	HIV
Gene Type	protein coding
HPA Location Info	Plasma membrane;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q8TF42
HGNC ID	HGNC:29884
VEGA ID	OTTHUMG00000166025
OMIM ID	609201
String ID	9606.ENSP00000284273
PharmGKB ID	PA162407840

Target gene [UBASH3B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000473	chr11	338	24	71	433	View
4000931	chr11	164	58	25	247	View
4002848	chr11	71	5	1	77	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of UBASH3B expression and immune infiltrating cell level correlation result in HIV+ samples
UBASH3B expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of UBASH3B expression and immune infiltrating cell level correlation result in HIV+ samples
UBASH3B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).