HIV Target gene Detail Information

> UBA6 Gene Search Result

Gene Information

Gene Name	UBA6
Gene ID	55236
Gene Full Name	ubiquitin like modifier activating enzyme 6
Gene Alias	E1-L2; MOP-4; UBE1L2
Transcripts	ENSG00000033178
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	A0AVT1
HGNC ID	HGNC:25581
VEGA ID	OTTHUMG00000129299
OMIM ID	611361
String ID	9606.ENSP00000313454
PharmGKB ID	PA162407690

Target gene [UBA6] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004587	chr4	26	16		42	View
4012998	chr4	4			4	View
4013699	chr4	3			3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of UBA6 expression and immune infiltrating cell level correlation result in HIV+ samples
UBA6 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of UBA6 expression and immune infiltrating cell level correlation result in HIV+ samples
UBA6 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).