HIV Target gene Detail Information

> TYW5 Gene Search Result

Gene Information

Gene Name	TYW5
Gene ID	129450
Gene Full Name	tRNA-yW synthesizing protein 5
Gene Alias	hTYW5; C2orf60
Transcripts	ENSG00000162971
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear bodies;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	A2RUC4
HGNC ID	HGNC:26754
VEGA ID	OTTHUMG00000132770
String ID	9606.ENSP00000346627
PharmGKB ID	PA162379298

Target gene [TYW5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004853	chr2	28	10		38	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TYW5 expression and immune infiltrating cell level correlation result in HIV+ samples
TYW5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).