HBV Target gene Detail Information

> TXLNB Gene Search Result


Gene Information
Gene Name TXLNB
Gene ID 167838
Gene Full Name taxilin beta
Gene Alias MDP77; LST001; C6orf198; dJ522B19.2
Transcripts ENSG00000164440
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q8N3L3
HGNC ID HGNC:21617
VEGA ID OTTHUMG00000015688
OMIM ID 611438
String ID 9606.ENSP00000351206
PharmGKB ID PA134878600
Target gene [TXLNB] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1001361 chr6 658 73 24 755 View
1401178 chr6 658 73 24 755 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of TXLNB expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
TXLNB expression: Low -> High
Lollipop of TXLNB expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of TXLNB expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of TXLNB expression and immune infiltrating cell level correlation result in HBV+ samples
TXLNB expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).