HBV Target gene Detail Information

> TUSC3 Gene Search Result

Gene Information

Gene Name	TUSC3
Gene ID	7991
Gene Full Name	tumor suppressor candidate 3
Gene Alias	M33; N33; MRT7; MRT22; MagT2; OST3A; D8S1992
Transcripts	ENSG00000104723
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters
Uniport_ID	Q13454
HGNC ID	HGNC:30242
VEGA ID	OTTHUMG00000094803
OMIM ID	601385
String ID	9606.ENSP00000424544
PharmGKB ID	PA128394537

Target gene [TUSC3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1009075	chr8	6	11		17	View
1016081	chr8		2		2	View
1017888	chr8				0	View
1401612	chr8				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of TUSC3 expression and immune infiltrating cell level correlation result in HBV+ samples
TUSC3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).