HBV Target gene Detail Information

> TUBB3 Gene Search Result

Gene Information

Gene Name	TUBB3
Gene ID	10381
Gene Full Name	tubulin beta 3 class III
Gene Alias	CDCBM; FEOM3; TUBB4; CDCBM1; CFEOM3; beta-4; CFEOM3A
Transcripts	ENSG00000258947
Virus	HBV
Gene Type	protein coding
HPA Location Info	Microtubules;Cytokinetic bridge;Mitotic spindle;
HPA Protein Class Info	Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q13509
HGNC ID	HGNC:20772
VEGA ID	OTTHUMG00000138985
OMIM ID	602661
Drugbank ID	BE0001415
PharmGKB ID	PA134953867

Target gene [TUBB3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1015524	chr16	2			2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of TUBB3 expression and immune infiltrating cell level correlation result in HBV+ samples
TUBB3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).