HIV Target gene Detail Information

> TTYH2 Gene Search Result

Gene Information

Gene Name	TTYH2
Gene ID	94015
Gene Full Name	tweety family member 2
Gene Alias	C17orf29
Transcripts	ENSG00000141540
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins, Transporters
Uniport_ID	Q9BSA4
HGNC ID	HGNC:13877
VEGA ID	OTTHUMG00000166018
OMIM ID	608855
String ID	9606.ENSP00000269346
PharmGKB ID	PA37823

Target gene [TTYH2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001216	chr17	82	23	87	192	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TTYH2 expression and immune infiltrating cell level correlation result in HIV+ samples
TTYH2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TTYH2 expression and immune infiltrating cell level correlation result in HIV+ samples
TTYH2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).