HIV Target gene Detail Information

> TTC9C Gene Search Result


Gene Information
Gene Name TTC9C
Gene ID 283237
Gene Full Name tetratricopeptide repeat domain 9C
Transcripts ENSG00000162222
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q8N5M4
HGNC ID HGNC:28432
VEGA ID OTTHUMG00000167607
String ID 9606.ENSP00000325266
PharmGKB ID PA142670685
Target gene [TTC9C] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4002356 chr11 93 5 98 View
4300033 chr11 19 3 2 24 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of TTC9C expression and immune infiltrating cell level correlation result in HIV+ samples
TTC9C expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of TTC9C expression and immune infiltrating cell level correlation result in HIV+ samples
TTC9C expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).