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HPV Target gene Detail Information

> TTC6 Gene Search Result


Gene Information
Gene Name TTC6
Gene ID 319089
Gene Full Name tetratricopeptide repeat domain 6
Gene Alias C14orf25; NCRNA00291
Transcripts ENSG00000139865
Virus HPV
Gene Type protein coding
HPA Location Info Centrosome;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q86TZ1
HGNC ID HGNC:19739
VEGA ID OTTHUMG00000157369
PharmGKB ID PA134868995
Target gene [TTC6] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5000194 chr14 146 154 363 663 View
5000374 chr14 154 38 63 255 View
5000400 chr14 48 181 3 232 View
5000621 chr14 96 20 1 117 View
5000930 chr14 62 5 67 View
5001051 chr14 55 55 View
5001858 chr14 20 1 21 View
5002188 chr14 14 14 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE65858 (GEO) Head and neck squamous cell carcinoma 270 Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)

> Dataset: GSE65858

HeatMap of cell type fractions in all samples Lollipop of TTC6 expression and immune infiltrating cell level correlation result in HPV+ samples
TTC6 expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of TTC6 expression and immune infiltrating cell level correlation result in HPV+ samples
TTC6 expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of TTC6 expression and immune infiltrating cell level correlation result in HPV+ samples
TTC6 expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of TTC6 expression and immune infiltrating cell level correlation result in HPV+ samples
TTC6 expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of TTC6 expression and immune infiltrating cell level correlation result in HPV+ samples
TTC6 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).