HIV Target gene Detail Information

> TTC39B Gene Search Result

Gene Information

Gene Name	TTC39B
Gene ID	158219
Gene Full Name	tetratricopeptide repeat domain 39B
Gene Alias	C9orf52
Transcripts	ENSG00000155158
Virus	HIV
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q5VTQ0
HGNC ID	HGNC:23704
VEGA ID	OTTHUMG00000019581
OMIM ID	613574
String ID	9606.ENSP00000422496
PharmGKB ID	PA162407261

Target gene [TTC39B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000503	chr9	252	78	94	424	View
4014797	chr9		2		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TTC39B expression and immune infiltrating cell level correlation result in HIV+ samples
TTC39B expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TTC39B expression and immune infiltrating cell level correlation result in HIV+ samples
TTC39B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).