HIV Target gene Detail Information

> TSPAN3 Gene Search Result

Gene Information

Gene Name	TSPAN3
Gene ID	10099
Gene Full Name	tetraspanin 3
Gene Alias	TM4-A; TM4SF8; TSPAN-3
Transcripts	ENSG00000140391
Virus	HIV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	O60637
HGNC ID	HGNC:17752
VEGA ID	OTTHUMG00000143728
OMIM ID	613134
String ID	9606.ENSP00000267970
PharmGKB ID	PA134913500

Target gene [TSPAN3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004182	chr15	2	46		48	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TSPAN3 expression and immune infiltrating cell level correlation result in HIV+ samples
TSPAN3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TSPAN3 expression and immune infiltrating cell level correlation result in HIV+ samples
TSPAN3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).