HBV Target gene Detail Information

> TSKU Gene Search Result


Gene Information
Gene Name TSKU
Gene ID 25987
Gene Full Name tsukushi, small leucine rich proteoglycan
Gene Alias TSK; E2IG4; LRRC54
Transcripts ENSG00000182704
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Nuclear bodies;Predicted to be secreted;
HPA Protein Class Info Predicted secreted proteins
Uniport_ID Q8WUA8
HGNC ID HGNC:28850
VEGA ID OTTHUMG00000165238
OMIM ID 608015
String ID 9606.ENSP00000434847
PharmGKB ID PA162407150
Target gene [TSKU] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005774 chr11 26 20 2 48 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of TSKU expression and immune infiltrating cell level correlation result in HBV+ samples
TSKU expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).