HIV Target gene Detail Information

> TSKS Gene Search Result

Gene Information

Gene Name	TSKS
Gene ID	60385
Gene Full Name	testis specific serine kinase substrate
Gene Alias	TSKS1; TSSKS; STK22S1; PPP1R161
Transcripts	ENSG00000126467
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9UJT2
HGNC ID	HGNC:30719
VEGA ID	OTTHUMG00000183249
OMIM ID	608253
String ID	9606.ENSP00000246801
PharmGKB ID	PA164727339

Target gene [TSKS] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001352	chr19	154	14	7	175	View
4004342	chr19	43	2	1	46	View
4008584	chr19	3	10	1	14	View
4014926	chr19	2			2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TSKS expression and immune infiltrating cell level correlation result in HIV+ samples
TSKS expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).