HIV Target gene Detail Information

> TSHZ3 Gene Search Result

Gene Information

Gene Name	TSHZ3
Gene ID	57616
Gene Full Name	teashirt zinc finger homeobox 3
Gene Alias	TSH3; ZNF537
Transcripts	ENSG00000121297
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Plasma membrane;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID	Q63HK5
HGNC ID	HGNC:30700
VEGA ID	OTTHUMG00000150184
OMIM ID	614119
String ID	9606.ENSP00000240587
PharmGKB ID	PA134887020

Target gene [TSHZ3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000600	chr19	256	11	84	351	View
4013392	chr19	3			3	View
4013393	chr19	3			3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TSHZ3 expression and immune infiltrating cell level correlation result in HIV+ samples
TSHZ3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TSHZ3 expression and immune infiltrating cell level correlation result in HIV+ samples
TSHZ3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).