HIV Target gene Detail Information

> TSHR Gene Search Result

Gene Information

Gene Name	TSHR
Gene ID	7253
Gene Full Name	thyroid stimulating hormone receptor
Gene Alias	LGR3; CHNG1; hTSHR-I
Transcripts	ENSG00000165409
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	P16473
HGNC ID	HGNC:12373
VEGA ID	OTTHUMG00000171429
OMIM ID	603372
String ID	9606.ENSP00000441235
Drugbank ID	BE0000490
PharmGKB ID	PA37042

Target gene [TSHR] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4011829	chr14	5	1		6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TSHR expression and immune infiltrating cell level correlation result in HIV+ samples
TSHR expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).